Sfoglia per Autore
In vitro and ex vivo characterization of sigma-1 and sigma-2 receptors: agonists and antagonists in biological assays
2009-01-01 Colabufo, Nicola Antonio; Perrone, Roberto; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Roperto, Sante; Roperto, Franco
F281, synthetic agonist of the sigma-2 receptor, induces Ca2+ efflux from the endoplasmic reticulum and mitochondria in SK-N-SH cells
2009-01-01 Cassano, Giuseppe; Gasparre, Giuseppe; Niso, Mauro; Contino, Marialessandra; Scalera, Vito Dom. E.; Colabufo, Nicola Antonio
Multi-drug-resistance-reverting agents: 2-aryloxazole and 2-arylthiazole derivatives as potent BCRP or MRP1 inhibitors
2009-01-01 Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, MARIA GRAZIA; Cantore, Mariangela; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Perrone, Roberto
The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists
2009-01-01 Perrone, MARIA GRAZIA; Bleve, L; Santandrea, E; Vitale, Paola; Niso, Mauro; Scilimati, Antonio
Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28)
2009-01-01 Berardi, Francesco; Abate, CARMEN rosa; Ferorelli, Savina; Uricchio, V; Colabufo, Nicola Antonio; Niso, Mauro; Perrone, Roberto
Perspectives of P-glycoprotein modulating agents in oncology and neurodegenerative diseases: pharmaceutical, biological and diagnostic potentials
2010-01-01 Colabufo, Nicola Antonio; Berardi, Francesco; Cantore, Mariangela; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Perrone, Roberto
Interaction of the sigma-2 receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer
2010-01-01 Abate, Carmen; Elenewski, J.; Niso, Mauro; Berardi, Francesco; Colabufo, Nicola Antonio; Azzariti, A.; Perrone, Roberto; Glennon, R. A.
DESIGN SYNTHESIS AND BIOLOGYCAL ACTIVITY OF NEW POTENT GALLOYL-BASED MRP1 INHIBITORS FOR REVERSING MDR
2010-01-01 Pellicani, R. Z.; Niso, Mauro; Stefanachi, Angela; Berardi, Francesco; Carotti, A; Cellamare, Saverio; Colabufo, Nicola Antonio; Perrone, R.
Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers
2011-01-01 Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto
Fluorescent Derivatives of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a Tool for Uptake and Cellular Localization Studies in Pancreatic Tumor Cells
2011-01-01 Abate, CARMEN rosa; Hornick, J; Spitzer, D; Hawkins, W; Niso, Mauro; Perrone, Roberto; Berardi, Francesco
1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity
2011-01-01 Abate, CARMEN rosa; Niso, Mauro; Contino, Marialessandra; Colabufo, Nicola Antonio; Ferorelli, Savina; Perrone, Roberto; Berardi, Francesco
EGFR tyrosine kinase inhibitors and multidrug resistance: perspectives
2011-01-01 Colabufo, Nicola Antonio; Contino, Marialessandra; Niso, Mauro; Berardi, Francesco; Leopoldo, Marcello; Perrone, Roberto
A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease
2012-01-01 Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A.
A Benzopyrane derivative as P-glycoprotein stimulator: a potential agent to decrease beta-amyloid accumulation in Alzheimer’s disease
2012-01-01 Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A.
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein.
2012-01-01 Pellicani, Rz; Stefanachi, Angela; Niso, Mauro; Carotti, Angelo; Leonetti, Francesco; Nicolotti, Orazio; Perrone, Roberto; Berardi, Francesco; Cellamare, Saverio; Colabufo, Nicola Antonio
2-Aminopyridine derivatives as potential sigma2 receptor antagonists
2012-01-01 Abate, CARMEN rosa; Ferorelli, Savina; Niso, Mauro; Lovicario, C; Infantino, V; Convertini, P; Perrone, Roberto; Berardi, Francesco
Investigations on the 1-(2-biphenyl)piperazine motif. Identification of new potent and selective ligands for the serotonin7 (5-HT7) receptor with agonist or antagonist action in vitro or ex vivo.
2012-01-01 Lacivita, Enza; Patarnello, D; Stroth, N; Caroli, A; Niso, Mauro; Contino, Marialessandra; De Giorgio, P; Di Pilato, P; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, R; Svenningsson, P; Hedlund, Pb; Leopoldo, Marcello
The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line
2013-01-01 Pagliarulo, Vincenzo; Ancona, Patrizia; Niso, Mauro; Colabufo, Nicola Antonio; Contino, Marialessandra; Cormio, Luigi; Azzariti, Amalia; Pagliarulo, Arcangelo
Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity
2013-01-01 Niso, Mauro; Abate, CARMEN rosa; Contino, Marialessandra; Ferorelli, Savina; Azzariti, Amalia; Perrone, Roberto; Colabufo, Nicola Antonio; Berardi, Francesco
Development of 3,4-dihydroisoquinolin-1(2H)-one derivatives for the Positron Emission Tomography (PET) imaging of sigma-2 receptors
2013-01-01 Abate, CARMEN rosa; Selivanova, S. V.; Müller, ; Krämer, S. D.; Schibli, R; Marottoli, R; Perrone, R; Berardi, Francesco; Niso, Mauro; Ametamey, S. M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| In vitro and ex vivo characterization of sigma-1 and sigma-2 receptors: agonists and antagonists in biological assays | 1-gen-2009 | Colabufo, Nicola Antonio; Perrone, Roberto; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Roperto, Sante; Roperto, Franco | |
| F281, synthetic agonist of the sigma-2 receptor, induces Ca2+ efflux from the endoplasmic reticulum and mitochondria in SK-N-SH cells | 1-gen-2009 | Cassano, Giuseppe; Gasparre, Giuseppe; Niso, Mauro; Contino, Marialessandra; Scalera, Vito Dom. E.; Colabufo, Nicola Antonio | |
| Multi-drug-resistance-reverting agents: 2-aryloxazole and 2-arylthiazole derivatives as potent BCRP or MRP1 inhibitors | 1-gen-2009 | Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, MARIA GRAZIA; Cantore, Mariangela; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Perrone, Roberto | |
| The tertiary amine nitrogen atom of piperazine sulfonamides as a novel determinant of potent and selective beta3-adrenoceptor agonists | 1-gen-2009 | Perrone, MARIA GRAZIA; Bleve, L; Santandrea, E; Vitale, Paola; Niso, Mauro; Scilimati, Antonio | |
| Exploring the importance of piperazine N-atoms for sigma-2 receptor affinity and activity in a series of analogs of 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) | 1-gen-2009 | Berardi, Francesco; Abate, CARMEN rosa; Ferorelli, Savina; Uricchio, V; Colabufo, Nicola Antonio; Niso, Mauro; Perrone, Roberto | |
| Perspectives of P-glycoprotein modulating agents in oncology and neurodegenerative diseases: pharmaceutical, biological and diagnostic potentials | 1-gen-2010 | Colabufo, Nicola Antonio; Berardi, Francesco; Cantore, Mariangela; Contino, Marialessandra; Inglese, Carmela; Niso, Mauro; Perrone, Roberto | |
| Interaction of the sigma-2 receptor ligand PB28 with the human nucleosome: computational and experimental probes of interaction with the H2A/H2B dimer | 1-gen-2010 | Abate, Carmen; Elenewski, J.; Niso, Mauro; Berardi, Francesco; Colabufo, Nicola Antonio; Azzariti, A.; Perrone, Roberto; Glennon, R. A. | |
| DESIGN SYNTHESIS AND BIOLOGYCAL ACTIVITY OF NEW POTENT GALLOYL-BASED MRP1 INHIBITORS FOR REVERSING MDR | 1-gen-2010 | Pellicani, R. Z.; Niso, Mauro; Stefanachi, Angela; Berardi, Francesco; Carotti, A; Cellamare, Saverio; Colabufo, Nicola Antonio; Perrone, R. | |
| Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers | 1-gen-2011 | Abate, CARMEN rosa; Niso, Mauro; Lacivita, Enza; Mosier, P. D.; Toscano, A.; Perrone, Roberto | |
| Fluorescent Derivatives of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) as a Tool for Uptake and Cellular Localization Studies in Pancreatic Tumor Cells | 1-gen-2011 | Abate, CARMEN rosa; Hornick, J; Spitzer, D; Hawkins, W; Niso, Mauro; Perrone, Roberto; Berardi, Francesco | |
| 1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and human Delta8─Delta7 sterol isomerase ligands with antiproliferative and P-glycoprotein inhibitory activity | 1-gen-2011 | Abate, CARMEN rosa; Niso, Mauro; Contino, Marialessandra; Colabufo, Nicola Antonio; Ferorelli, Savina; Perrone, Roberto; Berardi, Francesco | |
| EGFR tyrosine kinase inhibitors and multidrug resistance: perspectives | 1-gen-2011 | Colabufo, Nicola Antonio; Contino, Marialessandra; Niso, Mauro; Berardi, Francesco; Leopoldo, Marcello; Perrone, Roberto | |
| A Benzopyrane Derivative as a P-Glycoprotein Stimulator: A Potential Agent to Decrease β-Amyloid Accumulation in Alzheimer's Disease | 1-gen-2012 | Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A. | |
| A Benzopyrane derivative as P-glycoprotein stimulator: a potential agent to decrease beta-amyloid accumulation in Alzheimer’s disease | 1-gen-2012 | Contino, M.; Cantore, M.; Capparelli, E.; Perrone, M. G.; Niso, M.; Inglese, C.; Berardi, F.; Leopoldo, M.; Perrone, R.; Colabufo, N. A. | |
| Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein. | 1-gen-2012 | Pellicani, Rz; Stefanachi, Angela; Niso, Mauro; Carotti, Angelo; Leonetti, Francesco; Nicolotti, Orazio; Perrone, Roberto; Berardi, Francesco; Cellamare, Saverio; Colabufo, Nicola Antonio | |
| 2-Aminopyridine derivatives as potential sigma2 receptor antagonists | 1-gen-2012 | Abate, CARMEN rosa; Ferorelli, Savina; Niso, Mauro; Lovicario, C; Infantino, V; Convertini, P; Perrone, Roberto; Berardi, Francesco | |
| Investigations on the 1-(2-biphenyl)piperazine motif. Identification of new potent and selective ligands for the serotonin7 (5-HT7) receptor with agonist or antagonist action in vitro or ex vivo. | 1-gen-2012 | Lacivita, Enza; Patarnello, D; Stroth, N; Caroli, A; Niso, Mauro; Contino, Marialessandra; De Giorgio, P; Di Pilato, P; Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, R; Svenningsson, P; Hedlund, Pb; Leopoldo, Marcello | |
| The interaction of celecoxib with MDR transporters enhances the activity of mitomycin C in a bladder cancer cell line | 1-gen-2013 | Pagliarulo, Vincenzo; Ancona, Patrizia; Niso, Mauro; Colabufo, Nicola Antonio; Contino, Marialessandra; Cormio, Luigi; Azzariti, Amalia; Pagliarulo, Arcangelo | |
| Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: Hints for collateral sensitivity | 1-gen-2013 | Niso, Mauro; Abate, CARMEN rosa; Contino, Marialessandra; Ferorelli, Savina; Azzariti, Amalia; Perrone, Roberto; Colabufo, Nicola Antonio; Berardi, Francesco | |
| Development of 3,4-dihydroisoquinolin-1(2H)-one derivatives for the Positron Emission Tomography (PET) imaging of sigma-2 receptors | 1-gen-2013 | Abate, CARMEN rosa; Selivanova, S. V.; Müller, ; Krämer, S. D.; Schibli, R; Marottoli, R; Perrone, R; Berardi, Francesco; Niso, Mauro; Ametamey, S. M. |
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