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Titolo Data di pubblicazione Autore(i) File
Design, Synthesis, and Biological Evaluation of Imidazolyl Derivatives of 4,7-Disubstituted Coumarins as Selective Aromatase Inhibitors 1-gen-2011 Stefanachi, Angela; Favia, A. D.; Nicolotti, Orazio; Leonetti, F; Pisani, Leonardo; Catto, Marco; Zimmer, C; Hartmann, R. W.; Carotti, Angelo
Strategies of multi-objective optimization in drug discovery and development 1-gen-2011 Nicolotti, Orazio; Giangreco, I; Introcaso, A; Leonetti, Francesco; Stefanachi, Angela; Carotti, Angelo
Coumarin as a versatile scaffold to selectively target biologically relevant cytochrome P450 enzymes: aromatase, steroid 11β-hydroxylase and aldosterone synthase 1-gen-2011 Stefanachi, Angela; Favia, Ad; Nicolotti, Orazio; Leonetti, Francesco; Pisani, Leonardo; Catto, Marco; Zimmer, C; Hartmann, Rw; Cellamare, Saverio; Carotti, Angelo
BCR-ABL inhibitors in chronic myeloid leukemia: process chemistry and biochemical profile 1-gen-2011 Leonetti, Francesco; Stefanachi, Angela; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Cellamare, Saverio; Carotti, Angelo
Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity 1-gen-2011 CONEJO GARCÍA, A; Pisani, Leonardo; DEL CARMEN NÚÑEZ, M; Catto, Marco; Nicolotti, Orazio; Leonetti, Francesco; Campos, J; Gallo, M; Espinosa, A; Carotti, Angelo
New Strategies in the Chemotherapy of Leukemia: Eradicating Cancer Stem Cells in Chronic Myeloid Leukemia 1-gen-2012 Stefanachi, Angela; Leonetti, Francesco; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Cellamare, Saverio; Altomare, Cosimo Damiano; Carotti, Angelo
Design, synthesis and biological evaluation of 5-hydroxy, 5-substituted-pyrimidine-2,4,6-triones as potent inhibitors of gelatinases MMP-2 and MMP-9 1-gen-2012 Nicolotti, Orazio; Catto, Marco; Giangreco, Ilenia; Barletta, Maria; Leonetti, Francesco; Stefanachi, Angela; Pisani, Leonardo; Cellamare, Saverio; Tortorella, Paolo; Loiodice, Fulvio; Carotti, Angelo
Estimation of the Binding Free Energy by Linear Interaction Energy Models 1-gen-2012 Nicolotti, Orazio; Convertino, M; Leonetti, Francesco; Catto, Marco; Cellamare, Saverio; Carotti, Angelo
Toward a fragment-based approach to MMPs inhibitors: an expedite and efficient synthesis of N-hydroxylactams 1-gen-2012 Leonetti, Francesco; Muncipinto, G; Stefanachi, Angela; Nicolotti, Orazio; Cellamare, Saverio; Catto, Marco; Pisani, Leonardo; Pellegrino, G; Carotti, Angelo
Potent galloyl-based selective modulators targeting multidrug resistance associated protein 1 and P-glycoprotein. 1-gen-2012 Pellicani, Rz; Stefanachi, Angela; Niso, Mauro; Carotti, Angelo; Leonetti, Francesco; Nicolotti, Orazio; Perrone, Roberto; Berardi, Francesco; Cellamare, Saverio; Colabufo, Nicola Antonio
Computational methods for the design of potent aromatase inhibitors 1-gen-2013 Favia, Angelo Danilo; Nicolotti, Orazio; Stefanachi, Angela; Leonetti, Francesco; Carotti, Angelo
4-(Alkylamino)methyl-substituted coumarins as potent and selective AChE and MAO-B dual inhibitors with a therapeutic potential in neurodegenerative disorders 1-gen-2013 Pisani, L.; Catto, M.; Stefanachi, A.; Leonetti, F.; Campagna, F.; Nicolotti, O.; Soto-Otero, R.; Carotti, A.
Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase 1-gen-2013 Catto, Marco; Pisani, Leonardo; Leonetti, Francesco; Nicolotti, Orazio; Pesce, Paolo; Stefanachi, Angela; Cellamare, Saverio; Carotti, Angelo
Trimethoxybenzanilide-based P-glycoprotein modulators: an interesting case of lipophilicity tuning by intramolecular hydrogen bonding 1-gen-2014 Tardia, P; Stefanachi, Angela; Niso, Mauro; Stolfa, D. A.; Mangiatordi, G. F.; Alberga, D; Nicolotti, Orazio; Lattanzi, Gianluca; Carotti, Angelo; Leonetti, Francesco; Perrone, R; Berardi, Francesco; Azzariti, A; Colabufo, Nicola Antonio; Cellamare, Saverio
(EN) GALLOYL BENZAMIDE-BASED COMPOUNDS AS JNK MODULATORS (FR) COMPOSES A BASE DE GALLOYL BENZAMIDE UTILISES EN TANT QUE MODULATEURS DE JNK 1-gen-2014 Cellamare, Saverio; Carotti, Angelo; Stefanachi, Angela; Leonetti, Francesco; Nicolotti, Orazio; Catto, Marco; Pisani, Leonardo; Tardia, Piero; Introcaso, Antonellina; Valentina, Leo; Addabbo, Francesco; Montagnani, Monica; Nacci, Carmela
Galloyl benzamide-based compounds modulating tumour necrosis factor α-stimulated c-Jun N-terminal kinase and p38 mitogen-activated protein kinase signalling pathways 1-gen-2015 Leo, Valentina; Stefanachi, Angela; Nacci, Carmela; Leonetti, Francesco; DE CANDIA, Modesto; Carotti, Angelo; Altomare, Cosimo Damiano; Montagnani, Monica; Cellamare, Saverio
Multitarget-directed tricyclic pyridazinones as g protein-coupled receptor ligands and cholinesterase inhibitors. 1-gen-2015 Pau, A; Catto, Marco; Pinna, G; Frau, S; Murineddu, G; Asproni, B; Curzu, Mm; Pisani, Leonardo; Leonetti, Francesco; Loza, Mi; Brea, J; Pinna, Ga; Carotti, Angelo
Discovery of new 7-substituted-4-imidazolylmethyl coumarins and 4′-substituted-2-imidazolyl acetophenones open analogues as potent and selective inhibitors of steroid-11β-hydroxylase 1-gen-2015 Stefanachi, A; Hanke, N; Pisani, L; Leonetti, F; Nicolotti, O; Catto, M; Cellamare, S; Hartmann, Rw; Carotti, A
Mind the Gap ! A Journey towards Computational Toxicology 1-gen-2016 Mangiatordi, Giuseppe Felice; Alberga, Domenico; Altomare, Cosimo Damiano; Carotti, Angelo; Catto, Marco; Cellamare, Saverio; Gadaleta, Domenico; Lattanzi, Gianluca; Leonetti, Francesco; Pisani, Leonardo; Stefanachi, Angela; Trisciuzzi, Daniela; Nicolotti, Orazio
Design, synthesis, biological evaluation, NMR and DFT studies of structurally-simplified trimethoxy benzamides as P-glycoprotein selective inhibitors: the role of molecular flatness 1-gen-2016 Stefanachi, Angela; Mangiatordi, Giuseppe Felice; Tardia, Piero; Alberga, Domenico; Leonetti, Francesco; Niso, Mauro; Colabufo, Nicola Antonio; Adamo, Carlo; Nicolotti, Orazio; Cellamare, Saverio
Mostrati risultati da 61 a 80 di 114
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