Atmospheric pressure plasmas are acquiring more interest in biomedical applications where synthetic biodegradable polymers modified to impart cells adhesion properties play a crucial role. This paper shows a new approach for the bio functionalization of such materials: inclusion of a biomolecule during the plasma deposition. A dielectric barrier discharge system was used for the coatings deposition, coupled with an atomizer for the lactic acid/ elastin aerosol feeding. ATR-FTIR, XPS, and UV–VIS were used to investigate the chemical composition of the coatings. By properly tuning plasma parameters, a good retention of the monomer chemical structure could be obtained in the coatings, as well as the inclusion of elastin in its structure.
Atmospheric pressure plasma deposition of Poly Lactic Acid - like coatings with embedded elastin
DA PONTE, GABRIELLA;FANELLI, FIORENZA;FAVIA, Pietro
2014-01-01
Abstract
Atmospheric pressure plasmas are acquiring more interest in biomedical applications where synthetic biodegradable polymers modified to impart cells adhesion properties play a crucial role. This paper shows a new approach for the bio functionalization of such materials: inclusion of a biomolecule during the plasma deposition. A dielectric barrier discharge system was used for the coatings deposition, coupled with an atomizer for the lactic acid/ elastin aerosol feeding. ATR-FTIR, XPS, and UV–VIS were used to investigate the chemical composition of the coatings. By properly tuning plasma parameters, a good retention of the monomer chemical structure could be obtained in the coatings, as well as the inclusion of elastin in its structure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.