Neuroendocrine neoplasms (NENs) are classified as rare cancers. According to the WHO 2022 classification, gastroenteropancreatic well-differentiated NENs (GEP-NETs) are stratified into grade 1 (Ki-67 < 3%), grade 2 (3–20%), and grade 3 (>20%). While most GEP-NETs are grade 1 or lower-grade 2 (Ki-67 3–10%), both the incidence of these cancers and the availability of effective treatments decline as Ki-67 increases. [...]
Peptide receptor radionuclide therapy in G3 gastroenteropancreatic neuroendocrine tumors: a missed opportunity for European patients?
Cives, Mauro;
2025-01-01
Abstract
Neuroendocrine neoplasms (NENs) are classified as rare cancers. According to the WHO 2022 classification, gastroenteropancreatic well-differentiated NENs (GEP-NETs) are stratified into grade 1 (Ki-67 < 3%), grade 2 (3–20%), and grade 3 (>20%). While most GEP-NETs are grade 1 or lower-grade 2 (Ki-67 3–10%), both the incidence of these cancers and the availability of effective treatments decline as Ki-67 increases. [...]File in questo prodotto:
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