Prevalence of neglected tropical diseases among migrants living in Europe: A systematic review and meta-analysis. Travel Med Infect Dis. 2025 Mar-Apr;64:102823. doi: 10.1016/j.tmaid.2025.102823.

Background: Migration to Europe has intensified due to recent political conflicts, economic crises, and climate change, introducing an increased risk of neglected tropical diseases (NTDs) within this population. While NTDs typically impact tropical regions, their presence among migrants in Europe presents a growing challenge, compounded by limited research in this area. This study provides the first meta-analysis on the prevalence of NTDs in migrants across European nations. Methods: A systematic review and meta-analysis was conducted focusing on studies that included NTD prevalence among migrant populations in Europe, with data sourced until July 2024. Cross-sectional and longitudinal studies were eligible, with bias assessed using the Newcastle-Ottawa Scale. Prevalence rates for various NTDs were calculated using a random-effects model, and meta-regressions were performed to assess potential moderators like sample size, age, and gender. Results: A total of 148 studies comprising 228,798 migrants were analyzed. The most prevalent NTDs were strongyloidiasis (11.53 %) and schistosomiasis (10.8 %), with American trypanosomiasis also present. Dengue and lymphatic filariasis showed significant rates, though high heterogeneity was noted. Data quality was frequently low, with most studies at a high risk of bias. Conclusions: This study underscores the need for robust screening and diagnostic protocols in Europe for NTDs, particularly as clinician familiarity with these diseases is limited. Test-and-treat strategies appear promising, yet more comprehensive efforts are necessary. Establishing a European NTD registry could improve monitoring and management. Future studies should prioritize higher-quality data and address the barriers migrants face in accessing health services.