The increase of risk for hematopoietic cancer among pesticides operators particularly associated with specific compounds was reported by several case-controls studies. The retrospective semiquantitative estimates of the intensity of pesticides exposure allow the assessment of the trends of relative risks associated to the its variation. The aims of the present study are finalized to evaluate a modified version of a questionnaire used for the collection of data related to pesticides use modality in agriculture; to Apply the Dosemeci algorithm for the assessment of pesticides exposure intensity; to evaluate if the information of the specific questionnaire for the agriculture used in the Italian study on the haetiology of lymphoma are congruent with validated questionnaires and are useful to estimate the intensity of exposure to pesticides. The Alburkle questionnaire was previously validated on a sample of 40 pesticides users. The questionnaire reported data related to the different methods of pesticides use were codified and inserted in a data base of Microsoft Access® to obtain an exposure intensity score. A comparison of the items of the Arbukle questionnaire and the specific questionnaire for the agriculture was carried out. The results showed that only the use of back pesticides sprayers is associated with the exposure to levels higher than the median score (F= 8,58 p <= 0,006). This finding was confirmed in the multivariate analisys. The questionnaire comparison showed a not complete correspondence (60%) of the data of the specific questionnaire for the agriculture used in the Italian study on the haetiology of lymphoma, regarding the methods of pesticides spraying useful for the Dosemeci algorithm score assessment. In conclusion, the questionnaire used in the case-control study of HCC was suitable to the collection of data useful to the estimate of pesticides exposure in agriculture. The Dosemeci algorithm is able to properly quantify the exposure intensity. We need to increase the items of the specific questionnaire for the agriculture used in the Italian study on the haetiology of lymphoma to reach the right quantity of information useful for the assessment of the intensity score. The collection of data could be carried out by means of phone interviews.

VALUTAZIONE DEL QUESTIONARIO DI ARBUCKLE SU UN CAMPIONE DI IRRORATORI DI PESTICIDI E STUDIO DEI DETERMINANTI DELLA INTENSITA' DELL'ESPOSIZIONE A PESTICIDI

FERRI, Giovanni Maria;MUSTI, Marina;VIMERCATI, LUIGI;
2010-01-01

Abstract

The increase of risk for hematopoietic cancer among pesticides operators particularly associated with specific compounds was reported by several case-controls studies. The retrospective semiquantitative estimates of the intensity of pesticides exposure allow the assessment of the trends of relative risks associated to the its variation. The aims of the present study are finalized to evaluate a modified version of a questionnaire used for the collection of data related to pesticides use modality in agriculture; to Apply the Dosemeci algorithm for the assessment of pesticides exposure intensity; to evaluate if the information of the specific questionnaire for the agriculture used in the Italian study on the haetiology of lymphoma are congruent with validated questionnaires and are useful to estimate the intensity of exposure to pesticides. The Alburkle questionnaire was previously validated on a sample of 40 pesticides users. The questionnaire reported data related to the different methods of pesticides use were codified and inserted in a data base of Microsoft Access® to obtain an exposure intensity score. A comparison of the items of the Arbukle questionnaire and the specific questionnaire for the agriculture was carried out. The results showed that only the use of back pesticides sprayers is associated with the exposure to levels higher than the median score (F= 8,58 p <= 0,006). This finding was confirmed in the multivariate analisys. The questionnaire comparison showed a not complete correspondence (60%) of the data of the specific questionnaire for the agriculture used in the Italian study on the haetiology of lymphoma, regarding the methods of pesticides spraying useful for the Dosemeci algorithm score assessment. In conclusion, the questionnaire used in the case-control study of HCC was suitable to the collection of data useful to the estimate of pesticides exposure in agriculture. The Dosemeci algorithm is able to properly quantify the exposure intensity. We need to increase the items of the specific questionnaire for the agriculture used in the Italian study on the haetiology of lymphoma to reach the right quantity of information useful for the assessment of the intensity score. The collection of data could be carried out by means of phone interviews.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/52331
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