Editorial: Challenges in dementia care: a global perspective

After decades of research efforts, dementia care is still an open challenge. Some promising results come from disease modifying therapies in dementia due Alzheimer’s disease (AD) as the anti-amyloid antibodies lecanemab and donanemab (1). However the association between amyloid reduction strategies and a clinically meaningful improvement of cognitive outcomes remains questionable. Probably one of the few certainties is still the importance of the dementia prevention strategies (2). Indeed, an increasing knowledge and perception of the problem among people and healthcare systems, has led to observe in the last few years a promising trend toward reduction of incident dementia cases. However, nowadays there are around 57 million people worldwide living with dementia and the great burden of disease is attributable to the neurobehavioral symptoms. Such manifestations occur in most of individuals with dementia at some point of the disease history, increasing the caregiver burden and adversely affecting the quality of life for the patient and caregiver.