P4 Reproductive Medicine: Prediction, Prevention, Personalization, and Participation in Infertility Care

Infertility affects approximately 10–15% of couples in their reproductive age, and its impact is escalating globally. The IFFS has recently highlighted how fertility rates have dropped below replacement levels in many countries, with growing concern about population decline and its economic, social, and cultural impacts. The experts have emphasized the importance of family building policies, including access to fertility care, as crucial responses to these trends. Equitable access to reproductive technologies and family friendly policies are urgently needed to support individuals and couples in achieving their desired family sizes [1]. As reproductive medicine evolves, the integration of new therapies, advanced technologies, and personalized care approaches is reshaping the field, driving us toward P4 Reproductive Medicine—prediction, prevention, personalization, and participation. This Special Issue embraces some of the most recent findings in this scenario, highlighting how these four pillars are transforming infertility care and optimizing patient outcomes.