Regarding "Long-Term Reproductive Outcomes after Hysteroscopic Treatment of Dysmorphic Uteri in Women with Reproductive Failure: An European Multicenter Study" Reply Section snippets Ethical Aspect Since many years, our group has, at 3 medical centers, routinely offered hysteroscopic metroplasty to all the patients diagnosed with dysmorphic uterus who are suffering from reproductive issues resulting in unexplained infertility. The surgical procedures are performed in an outpatient setting, only by high-volume-experienced surgeons, with low public costs and low risks to the patients. Before performing the surgery, all patients receive adequate counseling regarding the potential risks, ... Diagnostic Criteria As already reported in the manuscript, we reiterate that the diagnosis of dysmorphic uterus was made by “hysteroscopy and 3-dimensional transvaginal ultrasonography” and not by hysteroscopy only, as stated by Ludwin et al. Regarding the study cohort, we acknowledge that some patients (n = 11) underwent surgery before the publication of the European Society of Human Reproduction and Embryology (ESHRE)/European Society for Gynaecological Endoscopy (ESGE) classification system of female genital ... Lack of a Control Group without Surgery Here, we reaffirm our statement made in the paper about a lack of a control group in our study (see “Limitations” section): “The absence of an untreated control group precluded us from making direct inferences as to the effect of the intervention on the reproductive outcomes.” In this respect, we acknowledge that the retrospective design and the lack of a control group were the main limitations of our study. We respectfully invite Ludwin et al. to read the limitations section of our ... Regarding Fig. 3 With respect for Ludwin et al., we found their allegations about our diagnostic failure inappropriate, unprofessional, and insulting, as some of us (A.D.S. and R.C.) have been actively involved in the development of the ESHRE/ESGE classification system (i.e., we perfectly know the diagnostic criteria of mullerian anomalies) and have devoted our clinical career helping women with infertility. The uterus displayed in Fig. 3 is unquestionably “dysmorphic” according to the ESHRE/ESGE criteria, as ...

Author's Reply

Vitagliano, Amerigo;Bettocchi, Stefano;
2020-01-01

Abstract

Regarding "Long-Term Reproductive Outcomes after Hysteroscopic Treatment of Dysmorphic Uteri in Women with Reproductive Failure: An European Multicenter Study" Reply Section snippets Ethical Aspect Since many years, our group has, at 3 medical centers, routinely offered hysteroscopic metroplasty to all the patients diagnosed with dysmorphic uterus who are suffering from reproductive issues resulting in unexplained infertility. The surgical procedures are performed in an outpatient setting, only by high-volume-experienced surgeons, with low public costs and low risks to the patients. Before performing the surgery, all patients receive adequate counseling regarding the potential risks, ... Diagnostic Criteria As already reported in the manuscript, we reiterate that the diagnosis of dysmorphic uterus was made by “hysteroscopy and 3-dimensional transvaginal ultrasonography” and not by hysteroscopy only, as stated by Ludwin et al. Regarding the study cohort, we acknowledge that some patients (n = 11) underwent surgery before the publication of the European Society of Human Reproduction and Embryology (ESHRE)/European Society for Gynaecological Endoscopy (ESGE) classification system of female genital ... Lack of a Control Group without Surgery Here, we reaffirm our statement made in the paper about a lack of a control group in our study (see “Limitations” section): “The absence of an untreated control group precluded us from making direct inferences as to the effect of the intervention on the reproductive outcomes.” In this respect, we acknowledge that the retrospective design and the lack of a control group were the main limitations of our study. We respectfully invite Ludwin et al. to read the limitations section of our ... Regarding Fig. 3 With respect for Ludwin et al., we found their allegations about our diagnostic failure inappropriate, unprofessional, and insulting, as some of us (A.D.S. and R.C.) have been actively involved in the development of the ESHRE/ESGE classification system (i.e., we perfectly know the diagnostic criteria of mullerian anomalies) and have devoted our clinical career helping women with infertility. The uterus displayed in Fig. 3 is unquestionably “dysmorphic” according to the ESHRE/ESGE criteria, as ...
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/518229
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