NUT carcinoma (NC) is an exceedingly rare and poorly differentiated carcinoma characterized by BDR4:NUTM1 gene translocation. Typically, the tumour affects young adults, and no standardized recommendations for therapeutic management are available since the clinical course is mostly dismal. We report the successful multimodal treatment in a 13-year-old boy affected by a primary chest NC with a novel NUTM1 rearrangement, that remains in complete continuous remission at 18 months from diagnosis.
Successful treatment of chest NUT-carcinoma in a paediatric patient with a novel NUTM1 rearrangement: case report and review of literature
Francesco De leonardis;Greco Miani Vittorio;Marulli Giuseppe;Patrizia Dall'Igna;Maruccia Michele;
2023-01-01
Abstract
NUT carcinoma (NC) is an exceedingly rare and poorly differentiated carcinoma characterized by BDR4:NUTM1 gene translocation. Typically, the tumour affects young adults, and no standardized recommendations for therapeutic management are available since the clinical course is mostly dismal. We report the successful multimodal treatment in a 13-year-old boy affected by a primary chest NC with a novel NUTM1 rearrangement, that remains in complete continuous remission at 18 months from diagnosis.File in questo prodotto:
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