: The chick embryo area vasculosa is an extraembryonic membrane that is commonly used in vivo to study both angiogenesis and anti-angiogenesis. This review article analyzes the possibility to use the area vasculosa as an in vivo assay for the screening of putative angiogenic and anti-angiogenic molecules in alternative to the chorioallantoic membrane, more useful to study tumor growth, angiogenesis, and metastasis, and the angiogenic activity of acellular scaffolds and organoids.
Chick embryo area vasculosa as an in vivo assay for the screening of angiogenic and anti-angiogenic molecules
Ribatti, Domenico
;Benagiano, Vincenzo
2023-01-01
Abstract
: The chick embryo area vasculosa is an extraembryonic membrane that is commonly used in vivo to study both angiogenesis and anti-angiogenesis. This review article analyzes the possibility to use the area vasculosa as an in vivo assay for the screening of putative angiogenic and anti-angiogenic molecules in alternative to the chorioallantoic membrane, more useful to study tumor growth, angiogenesis, and metastasis, and the angiogenic activity of acellular scaffolds and organoids.File in questo prodotto:
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