OBJECTIVE: Polycystic ovary syndrome is associated with reproductive and metabolic dysfunction; in fact, treatment aims in PCOS focus on optimizing healthy weight, im- proving underlying hormonal disturbances, pre- venting future reproductive and metabolic com- plications, and improving quality of life. PATIENTS AND METHODS: This pilot study con- sidered 8 overweight females (BMI > 30) in repro- ductive age with PCOS. Patients were treated with a galenical preparation mixture containing resver- atrol and alpha-lipoic acid in association with vita- min D, B and folic acid for 12 weeks, after which an- thropometric assessment was conducted. RESULTS: After 12 weeks of treatment, BMI, anthropometry and bioimpedance parameters were all reduced in the treated patients com- pared to baseline. CONCLUSIONS: The present nutraceutical combination resulted beneficial for improving the metabolic profile of women with PCOS, paving the way for new nutraceutical strategies for the management of metabolic disturbances in PC
Effects of a combination of resveratrol and alpha-lipoic acid on body weight and adipose composition in women with PCOS: a preliminary pilot study
Lupica G.;Vimercati A.;Dellino M.;
2022-01-01
Abstract
OBJECTIVE: Polycystic ovary syndrome is associated with reproductive and metabolic dysfunction; in fact, treatment aims in PCOS focus on optimizing healthy weight, im- proving underlying hormonal disturbances, pre- venting future reproductive and metabolic com- plications, and improving quality of life. PATIENTS AND METHODS: This pilot study con- sidered 8 overweight females (BMI > 30) in repro- ductive age with PCOS. Patients were treated with a galenical preparation mixture containing resver- atrol and alpha-lipoic acid in association with vita- min D, B and folic acid for 12 weeks, after which an- thropometric assessment was conducted. RESULTS: After 12 weeks of treatment, BMI, anthropometry and bioimpedance parameters were all reduced in the treated patients com- pared to baseline. CONCLUSIONS: The present nutraceutical combination resulted beneficial for improving the metabolic profile of women with PCOS, paving the way for new nutraceutical strategies for the management of metabolic disturbances in PCI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
