Acute kidney injury is a serious complication in surgical and critical care patients and carries an increased risk of mortality and additional hospital costs. Hemodynamic optimization to reduce mortality in critically ill patients with or at risk for AKI is supported by high-level evidence. However, several points of debate are still open, including the type of fluid to be used to reach the hemodynamic targets, the inotropic support, the choice of the monitoring tool, as well as of the hemodynamic variables to be targeted, and which subgroup of the high-risk surgical population could benefit most from a goal-directed therapy approach.
Perioperative hemodynamic optimization to reduce acute kidney injury and mortality in surgical patients
Brienza N.;Giglio M.;
2016-01-01
Abstract
Acute kidney injury is a serious complication in surgical and critical care patients and carries an increased risk of mortality and additional hospital costs. Hemodynamic optimization to reduce mortality in critically ill patients with or at risk for AKI is supported by high-level evidence. However, several points of debate are still open, including the type of fluid to be used to reach the hemodynamic targets, the inotropic support, the choice of the monitoring tool, as well as of the hemodynamic variables to be targeted, and which subgroup of the high-risk surgical population could benefit most from a goal-directed therapy approach.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.