The 1,3-dipolar cycloaddition reaction between alkanone enolates and azides proceeds smoothly and regioselectively in eco-friendly eutectic mixtures to yield densely functionalized 1,2,3-triazoles. Pharmacologically active triazoles have also been targeted directly in DESs via telescoped, one-pot cycloaddition/reduction processes.
1,3‐Dipolar Cycloaddition of Alkanone Enolates with Azides in Deep Eutectic Solvents for the Metal‐Free Regioselective Synthesis of Densely Functionalized 1,2,3‐Triazoles
Cicco, Luciana;Perna, Filippo Maria;Falcicchio, Aurelia;Salomone, Antonio;Capriati, Vito
;Vitale, Paola
2022-01-01
Abstract
The 1,3-dipolar cycloaddition reaction between alkanone enolates and azides proceeds smoothly and regioselectively in eco-friendly eutectic mixtures to yield densely functionalized 1,2,3-triazoles. Pharmacologically active triazoles have also been targeted directly in DESs via telescoped, one-pot cycloaddition/reduction processes.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
