Orofacial pain is a universal predicament, afflicting millions of individuals worldwide. Research on the molecular mechanisms of orofacial pain has predominately focused on the role of neurons underlying nociception. Orofacial pain can arise from different regions and etiologies. Temporomandibular disorders are the most prevalent orofacial pain conditions for which patients seek treatment. Pain on weak tactile stimulation is expected if dentinal terminate synaptically on trigeminal brainstem neurons that deliver a pain message to higher brain centers. Further studies are needed.

Toothache and brain: Any connections?

Converti I.;Maggiore M. E.;Ceci S.;De Giacomo A.;Coscia M. F.;Del Prete R.;
2022-01-01

Abstract

Orofacial pain is a universal predicament, afflicting millions of individuals worldwide. Research on the molecular mechanisms of orofacial pain has predominately focused on the role of neurons underlying nociception. Orofacial pain can arise from different regions and etiologies. Temporomandibular disorders are the most prevalent orofacial pain conditions for which patients seek treatment. Pain on weak tactile stimulation is expected if dentinal terminate synaptically on trigeminal brainstem neurons that deliver a pain message to higher brain centers. Further studies are needed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/409319
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