Editorial: Probiotics in Children Health

There is a growing body of evidence linking human health to the activity and composition 83 of gut microbiota as well as its alteration to intestinal and systemic diseases. In the last 84 years, functional gastrointestinal disorders, inflammatory, allergic, and autoimmune conditions, 85 metabolic syndrome, and neurological and behavioral diseases have all been associated with 86 microbiota unbalance, the so-called “dysbiosis” . The perinatal period and early life should be 87 considered as extremely vulnerable ages for the establishment of physiological microbiota and its 88 consequent programming of immune and metabolic responses.