Haemophilia is an X-linked bleeding disorder and is characterised by repeated bleeding, especially in joints. The current management of haemophilia is based on the replacement therapy with intravenous clotting factor and includes plasma-derived and recombinant factor concentrates. The early treatment in pediatrics age has been recognised as an important determinant of better physical development, and several studies have demonstrated that primary prophylaxis has a positive and significant impact on the quality of life and the prevention of arthropathy in haemophiliac children. Also, home treatment has shown to improve both life expectancy and quality of life of patients with haemophilia.
Uncovered needs in the management of inherited bleeding disorders in Italy.
GIORDANO, Paola;
2014-01-01
Abstract
Haemophilia is an X-linked bleeding disorder and is characterised by repeated bleeding, especially in joints. The current management of haemophilia is based on the replacement therapy with intravenous clotting factor and includes plasma-derived and recombinant factor concentrates. The early treatment in pediatrics age has been recognised as an important determinant of better physical development, and several studies have demonstrated that primary prophylaxis has a positive and significant impact on the quality of life and the prevention of arthropathy in haemophiliac children. Also, home treatment has shown to improve both life expectancy and quality of life of patients with haemophilia.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
