Hysterectomy in patients with previous cesarean section: comparison between laparoscopic and vaginal approaches.

OBJECTIVE: To evaluate surgery-related outcomes of laparoscopic (LH) and vaginal hysterectomy (VH) in patients with a history of previous cesarean section (CS). STUDY DESIGN: Data on 289 consecutive patients with a history of CS undergoing VH (n=49, 17%) and LH (n=219, 76%) were collected. Basic descriptive statistics, univariate and multivariate analyses were performed to evaluate surgery-related outcomes. A propensity-matched algorithm was applied in order to reduce allocation biases between groups. RESULTS: Patients undergoing LH were more likely to have a history of multiple cesarean sections (44% vs. 18%; p=0.001). Additionally, uterine weight was greater among patients undergoing LH than VH (median weight: 235 (range, 45-2830) vs. 150 (range, 40-710)g; p<0.001). Three patients in each group experienced procedural bladder injuries (3/219 (1%) vs. 3/49 (6%); p=0.07; RR: 1.65; 95%CI: 0.74, 3.68). The rate of grade 3 or worse postoperative complications was balanced between LH and VH (1% vs. 0%; p=1.00). Patients undergoing LH experienced a shorter length of hospital stay in comparison to patients undergoing VH (1 vs. 2 days; p=0.02). Considering the overall population, we observed via multivariate analysis that age (OR: 1.003 (95%CI: 1.001, 1.004) per 10-year increase in age; p=0.002), VH (OR: 17.80 (95%CI: 1.762, 180,378); p=0.01) and number of cesarean sections≥2 (OR: 27.70 (95%CI: 1.976, 388,285); p=0.01) increased the risk of developing bladder injuries during hysterectomy. CONCLUSIONS: LH is a safe and feasible procedure in patients with previous CS, and it is associated with a low bladder injury rate.