A method is provided for detecting or diagnosing genomic instability in an individual by determining the difference in mutation frequency between a non-conserved genomic region and an ultra-conserved genomic region (UCR), where a statistically significant increase in mutation frequency in the non-conserved region as compared to the UCR establishes a likelihood of genomic instability in the individual.
Method for Detecting or Diagnosing Genomic Instability
DE GRASSI, ANNA
2009-01-01
Abstract
A method is provided for detecting or diagnosing genomic instability in an individual by determining the difference in mutation frequency between a non-conserved genomic region and an ultra-conserved genomic region (UCR), where a statistically significant increase in mutation frequency in the non-conserved region as compared to the UCR establishes a likelihood of genomic instability in the individual.File in questo prodotto:
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