Penile metastasization is an uncommon condition, mostly derived from primitive advanced abdominal cancers, with disabling symptoms. Palliative treatment, in reason of poor prognosis patients, is frequently surgical with destructive management. We report two cases of penile metastasis, from primitive prostatic adenocarcinoma and primitive urothelial carcinoma, effectively managed with radiation treatment at our institution. A three-dimensional conformal radiation therapy with 42 Gy to the planning target volume in 14 fractions was delivered. Radiation treatment was safely delivered, with low toxicity profile and achieved adequate symptoms control without compromising genitourinary functions. Radiation therapy should be considered in management of rare penile metastases.

Radiotherapy is effective in the management of rare penile metastases: Two case reports

Sardaro A.;
2021-01-01

Abstract

Penile metastasization is an uncommon condition, mostly derived from primitive advanced abdominal cancers, with disabling symptoms. Palliative treatment, in reason of poor prognosis patients, is frequently surgical with destructive management. We report two cases of penile metastasis, from primitive prostatic adenocarcinoma and primitive urothelial carcinoma, effectively managed with radiation treatment at our institution. A three-dimensional conformal radiation therapy with 42 Gy to the planning target volume in 14 fractions was delivered. Radiation treatment was safely delivered, with low toxicity profile and achieved adequate symptoms control without compromising genitourinary functions. Radiation therapy should be considered in management of rare penile metastases.
2021
La métastase pénienne est une affection rare, principalement dérivée de cancers abdominaux évolués primitifs, avec des symptômes invalidants. Le traitement palliatif, en raison du pronostic défavorable, est souvent chirurgical avec une prise en charge destructive. Nous rapportons deux cas de métastases péniennes, d’adénocarcinome prostatique primitif et de carcinome urothélial primitif, gérées efficacement par radiothérapie dans notre établissement. Une radiothérapie conformationnelle tridimensionnelle de 42 Gy dans le volume cible prévisionnel en 14 fractions a été délivrée. La radiothérapie a été administrée en toute sécurité, avec un faible profil de toxicité et a permis un contrôle adéquat des symptômes sans compromettre les fonctions génito-urinaires. La radiothérapie doit être envisagée dans la prise en charge des rares métastases péniennes.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/371590
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