The external quenching method based on flow microreactors allows the generation and use of short-lived fluoro-substituted methyllithium reagents, such as fluoromethyllithium, fluoroiodomethyllithium, and fluoroiodostannylmethyllithium. Highly chemoselective reactions have been developed, opening new opportunities in the synthesis of fluorinated molecules using fluorinated organometallics.
Fluoro-Substituted Methyllithium Chemistry: External Quenching Method Using Flow Microreactors
Colella M.Membro del Collaboration Group
;Degennaro L.Investigation
;Luisi R.
Writing – Original Draft Preparation
;
2020-01-01
Abstract
The external quenching method based on flow microreactors allows the generation and use of short-lived fluoro-substituted methyllithium reagents, such as fluoromethyllithium, fluoroiodomethyllithium, and fluoroiodostannylmethyllithium. Highly chemoselective reactions have been developed, opening new opportunities in the synthesis of fluorinated molecules using fluorinated organometallics.File in questo prodotto:
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