Efficacy of combined sea salt based oral rinse with xylitol in improving healing process and oral hygiene among diabetic population after oral surgery

Diabetes may be considered a disease characterized by dysmetabolic and increased levels of blood glucose. The impaired metabolism of glucose, lipids, and proteins produces alterations in macro- and micro-vascular circulation, giving rise to the risk of several complications in patients with diabetes, including retinopathy, neuropathy, nephropathy, cardiovascular complications, and delayed wound healing. Periodontal disease is a chronic inflammatory disease of tissues that supports and affects the teeth and the jaws. Substantial evidence suggests a relationship between diabetes and periodontal disease. Many studies in several populations have demonstrated that diabetic patients tend to have a higher prevalence of and more severe periodontitis than non-diabetics. Hyperglycaemia, a key abnormality in diabetes, plays an important role in the development of inflammation in diabetic complications. It has been demonstrated that high blood sugar promotes inflammation and inhibits wound healing by altering angiogenesis. Periodontal lesions are observed in the presence of plaque and tartar and are more serious in diabetics. Therefore, it seems that proper hygiene and adequate plaque control can play a therapeutic role not only in bacterial control, but also in the resolution of oral surgery procedures. [...]