The current diagnostic work-up and monitoring of idiopathic pulmonary fibrosis (IPF) is often invasive and time consuming. Breath analysis by e-nose technology has shown potential in the diagnosis of numerous respiratory diseases. In this pilot study, we investigated whether exhaled breath analysis by an e-nose could discriminate among patients with IPF, healthy controls and COPD. Second, we verified whether these classification could be repeated in a set of newly recruited patients as external validation. Third, we evaluated any significant relationships between exhaled VOCs and Bronchoalveolar lavage fluid (BALF) in IPF patients.

Exhaled Volatile Organic Compounds analysis by e-nose can detect Idiopathic Pulmonary Fibrosis

Dragonieri, Silvano
;
Scioscia, Giulia;Quaranta, Vitaliano Nicola;Carratu, Pierluigi;Venuti, Maria Pia;Falcone, Michele;Carpagnano, Giovanna E;Resta, Onofrio;
2020

Abstract

The current diagnostic work-up and monitoring of idiopathic pulmonary fibrosis (IPF) is often invasive and time consuming. Breath analysis by e-nose technology has shown potential in the diagnosis of numerous respiratory diseases. In this pilot study, we investigated whether exhaled breath analysis by an e-nose could discriminate among patients with IPF, healthy controls and COPD. Second, we verified whether these classification could be repeated in a set of newly recruited patients as external validation. Third, we evaluated any significant relationships between exhaled VOCs and Bronchoalveolar lavage fluid (BALF) in IPF patients.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11586/299651
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