Oral squamous cell carcinoma in patients under 20 years of age is extremely rare, the alveolar gingiva being the most frequently affected site. The metachronous occurrence (eight years later) of a dentinogenic ghost cell tumour of the anterior maxilla in the same patient has never been previously reported. The patient had been diagnosed with a poorly differentiated squamous cell carcinoma of the ventral tongue when 12 years of age and was treated by en-block resection with functional neck dissection. Eight years later, he showed a dentinogenic ghost cell tumour in the anterior maxilla, associated with an impacted central incisor, which was treated by conservative surgery with wide margins; the patient has remained free of disease, without recurrence, at the one-year follow-up. Though extremely rare, malignancies should be considered in the diagnostic work-up of paediatric/adolescent patients with head and neck neoplasms. Additional difficulties arise when dealing with multiple tumours, both under a differential diagnostic point of view and for the surgical management, due to the lack of unanimously accepted guidelines for treatment and follow-up. To the best of our knowledge, oral squamous cell carcinoma and dentinogenic ghost cell tumour are unrelated to each other and may represent a casual combination, which raises additional questions as to the clinical management.
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|Titolo:||DENTINOGENIC GHOST CELL TUMOUR IN A 20-YEAR-OLD MALE WITH PREVIOUS SQUAMOUS CELL CARCINOMA OF THE TONGUE|
|Data di pubblicazione:||2019|
|Appare nelle tipologie:||1.1 Articolo in rivista|