Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial

Male, Christoph; Lensing, Anthonie W A; Palumbo, Joseph S; Kumar, Riten; Nurmeev, Ildar; Hege, Kerry; Bonnet, Damien; Connor, Philip; Hooimeijer, Hélène L; Torres, Marcela; Chan, Anthony K C; Kenet, Gili; Holzhauer, Susanne; Santamaría, Amparo; Amedro, Pascal; Chalmers, Elizabeth; Simioni, Paolo; Bhat, Rukhmi V; Yee, Donald L; Lvova, Olga; Beyer-Westendorf, Jan; Biss, Tina T; Martinelli, Ida; Saracco, Paola; Peters, Marjolein; Kállay, Krisztián; Gauger, Cynthia A; Massicotte, M Patricia; Young, Guy; Pap, Akos F; Majumder, Madhurima; Smith, William T; Heubach, Jürgen F; Berkowitz, Scott D; Thelen, Kirstin; Kubitza, Dagmar; Crowther, Mark; Prins, Martin H; Monagle,; Collaborators: Molinari AC, Paul.; Nowak Göttl, U; Chain, J; Robertson, J; Thom, K; Streif, W; Schwarz, R; Schmitt, K; Grangl, G; Van Damme, A; Maes, P; Labarque, V; Petrilli, A; Loggeto, S; Azeka, E; Brandao, L; Le, D; Sabapathy, C; Giordano, P; Wu, R; Ding, J; Huang, W; Mao, J; Lähteenmäki, P; Amedro, P; Decramer, S; Bernig, T; Chada, M; Chan, G; Kally, K; Nolan, B; Revel-Vilk, S; Tamary, H; Levin, C; Tormene, D; Abbattista, M; Artoni, A; Ikeyama, T; Inuzuka, R; Yasukochi, S; Morales Soto, M; Solis Labastida KA,; Suijker, Mh; Bartels, M; Tamminga, Ry; Van Ommen CH,; Te Loo DM,; Anjos, R; Zubarovskaya, L; Popova, N; Samochatova, E; Belogurova, M; Svirin, P; Shutova, T; Lebedev, V; Barbarash, O; Koh, Pl; Mei, Jc; Podracka, L; Berrueco, R; Fernandez, Mf; Frisk, T; Grunt, S; Rischewski, J; Albisetti-Pedroni, M; Antmen, A; Tokgoz, H; Karakas, Z; Chalmers, E; Motwani, J; Williams, M; Grainger, J; Payne, J; Richards, M; Baird, S; Bhatnagar, N; Aramburo, A; Crary, S; Wynn, T; Carpenter, S; Hege, K; Ahuja, S; Goldenberg, N; Woods, G; Godder, K; Scott-Emuakpor, A; Roach, G; Raffini, L; Shah, N; Shah, S; Thornburg, C; Zia, A; Berkow, R.

doi:10.1016/S2352-3026(19)30219-4

Treatment of venous thromboembolism in children is based on data obtained in adults with little direct documentation of its efficacy and safety in children. The aim of our study was to compare the efficacy and safety of rivaroxaban versus standard anticoagulants in children with venous thromboembolism.

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Titolo:	Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial
Autori:	Male, Christoph Lensing, Anthonie W A Palumbo, Joseph S Kumar, Riten Nurmeev, Ildar Hege, Kerry Bonnet, Damien Connor, Philip Hooimeijer, Hélène L Torres, Marcela Chan, Anthony K C Kenet, Gili Holzhauer, Susanne Santamaría, Amparo Amedro, Pascal Chalmers, Elizabeth Simioni, Paolo Bhat, Rukhmi V Yee, Donald L Lvova, Olga Beyer-Westendorf, Jan Biss, Tina T Martinelli, Ida Saracco, Paola Peters, Marjolein Kállay, Krisztián Gauger, Cynthia A Massicotte, M Patricia Young, Guy Pap, Akos F Majumder, Madhurima Smith, William T Heubach, Jürgen F Berkowitz, Scott D Thelen, Kirstin Kubitza, Dagmar Crowther, Mark Prins, Martin H Monagle Paul. Collaborators: Molinari AC Nowak Göttl U Chain J Robertson J Thom K Streif W Schwarz R Schmitt K Grangl G Van Damme A Maes P Labarque V Petrilli A Loggeto S Azeka E Brandao L Le D Sabapathy C GIORDANO, Paola Wu R Ding J Huang W Mao J Lähteenmäki P Amedro P Decramer S Bernig T Chada M Chan G Kally K Nolan B Revel-Vilk S Tamary H Levin C Tormene D Abbattista M Artoni A Ikeyama T Inuzuka R Yasukochi S Morales Soto M Solis Labastida KA Suijker MH Bartels M Tamminga RY Van Ommen CH Te Loo DM Anjos R Zubarovskaya L Popova N Samochatova E Belogurova M Svirin P Shutova T Lebedev V Barbarash O Koh PL Mei JC Podracka L Berrueco R Fernandez MF Frisk T Grunt S Rischewski J Albisetti-Pedroni M Antmen A Tokgoz H Karakas Z Chalmers E Motwani J Williams M Grainger J Payne J Richards M Baird S Bhatnagar N Aramburo A Crary S Wynn T Carpenter S Hege K Ahuja S Goldenberg N Woods G Godder K Scott-Emuakpor A Roach G Raffini L Shah N Shah S Thornburg C Zia A Berkow R. mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	2019
Rivista:	THE LANCET. HAEMATOLOGY
Abstract:	Treatment of venous thromboembolism in children is based on data obtained in adults with little direct documentation of its efficacy and safety in children. The aim of our study was to compare the efficacy and safety of rivaroxaban versus standard anticoagulants in children with venous thromboembolism.
Handle:	http://hdl.handle.net/11586/251215
Appare nelle tipologie:	1.1 Articolo in rivista

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