Randomized controlled clinical trials represent the gold standard of research into health-care interventions but conducting a randomized trial requires careful planning, structures and procedures. The conduct of a clinical trial is a collaborative effort between investigators, participants and a range of professionals involved both centrally and locally in the coordination and execution of the study. In this article, the key steps to conducting a randomized controlled trial are summarized. Clinical trials require extensive management and coordination in order to provide appropriate answers to clinical questions about health-care practices and to comply with the standards of good clinical practice. This article describes the steps required to conduct a randomized controlled trial. © 2010 Asian Pacific Society of Nephrology.
How to conduct a randomized trial
Strippoli G
2010-01-01
Abstract
Randomized controlled clinical trials represent the gold standard of research into health-care interventions but conducting a randomized trial requires careful planning, structures and procedures. The conduct of a clinical trial is a collaborative effort between investigators, participants and a range of professionals involved both centrally and locally in the coordination and execution of the study. In this article, the key steps to conducting a randomized controlled trial are summarized. Clinical trials require extensive management and coordination in order to provide appropriate answers to clinical questions about health-care practices and to comply with the standards of good clinical practice. This article describes the steps required to conduct a randomized controlled trial. © 2010 Asian Pacific Society of Nephrology.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
