Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant gut might have a role in feeding intolerance and pathogenesis of necrotizing enterocolitis. Despite several clinical trials and meta-analyses, it is still not clear if modulation of maternal and neonatal microbiota with probiotic supplementation decreases the risk of preterm birth and its complications.

Dysbiosis and Prematurity: Is There a Role for Probiotics?

Baldassarre, Maria Elisabetta
Conceptualization
;
Di Mauro, Antonio
Writing – Review & Editing
;
Capozza, Manuela
Methodology
;
Rizzo, Valentina
Investigation
;
Schettini, Federico
Investigation
;
Panza, Raffaella
Writing – Review & Editing
;
Laforgia, Nicola
Supervision
2019-01-01

Abstract

Healthy microbiota is a critical mediator in maintaining health and it is supposed that dysbiosis could have a role in the pathogenesis of a number of diseases. Evidence supports the hypothesis that maternal dysbiosis could act as a trigger for preterm birth; aberrant colonization of preterm infant gut might have a role in feeding intolerance and pathogenesis of necrotizing enterocolitis. Despite several clinical trials and meta-analyses, it is still not clear if modulation of maternal and neonatal microbiota with probiotic supplementation decreases the risk of preterm birth and its complications.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/230719
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