A general procedure for the synthesis of the title compounds has been devised starting from the available 2-halophenylethyl azides, by means of click reactions with trimethylsilylacetylene or 1-trimethylsilyl-1,3-butadiyne followed by a transition metal-catalyzed functionalization of C–H bond. A further extension of this procedure led us to devise the synthesis of more complex 4,4¢-bitriazole-fused dihydroisoquinolines
A general procedure for the synthesis of alkyl- and arylethynyl-1,2,3-triazole-fused dihydroisoquinolines
PUNZI, Angela;
2012-01-01
Abstract
A general procedure for the synthesis of the title compounds has been devised starting from the available 2-halophenylethyl azides, by means of click reactions with trimethylsilylacetylene or 1-trimethylsilyl-1,3-butadiyne followed by a transition metal-catalyzed functionalization of C–H bond. A further extension of this procedure led us to devise the synthesis of more complex 4,4¢-bitriazole-fused dihydroisoquinolinesFile in questo prodotto:
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