Background & Objective: A green one-pot synthesis of oleic acid (1) derivatives is promoted by Rare Earth Metal (REM) triflates and commercial Molybdenum dioxo dichloride (MoCl 2 O 2 ) in the presence hydrogen peroxide as a green oxidant. Results: The protocol permits to govern the oxidation selectivity by simply choosing the proper combination of Mo and Sc catalysts. Conclusion: Methyl oleate epoxide 2a and azelaic acid 6 thus obtained are valuable industrial intermediates for synthesizing bio-compostable plastics, plasticizers of PVC, lubricating oils, cosmetics and pharmaceuticals (bactericides, anti-inflammatories, etc.).

Green procedure for one-pot synthesis of azelaic acid derivatives using metal catalysis

Laurenza, Amelita Grazia
Investigation
;
Casiello, Michele
Investigation
;
Caputo, Daniela
Investigation
;
Catucci, Lucia
Formal Analysis
;
Rizzi, Vito
Formal Analysis
;
D'Accolti, Lucia
Writing – Original Draft Preparation
;
Nacci, Angelo
Conceptualization
2018

Abstract

Background & Objective: A green one-pot synthesis of oleic acid (1) derivatives is promoted by Rare Earth Metal (REM) triflates and commercial Molybdenum dioxo dichloride (MoCl 2 O 2 ) in the presence hydrogen peroxide as a green oxidant. Results: The protocol permits to govern the oxidation selectivity by simply choosing the proper combination of Mo and Sc catalysts. Conclusion: Methyl oleate epoxide 2a and azelaic acid 6 thus obtained are valuable industrial intermediates for synthesizing bio-compostable plastics, plasticizers of PVC, lubricating oils, cosmetics and pharmaceuticals (bactericides, anti-inflammatories, etc.).
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11586/226756
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