The aim of our study is to focus on hTERT (human Telomerase Reverse Transcriptase) expression to identify tumoral tissue after a comparison to TP53 and KRAS. More than 85% of cancer cells contain genetic aberrations and also overexpression of hTERT, and, in fact, the promoter of hTERT characterizes all malignant cells.

Study of the role of telomerase in colorectal cancer: preliminary report and literature review

Minafra, M;Laforgia, R;Lattarulo, S;Fabiano, G.
2017

Abstract

The aim of our study is to focus on hTERT (human Telomerase Reverse Transcriptase) expression to identify tumoral tissue after a comparison to TP53 and KRAS. More than 85% of cancer cells contain genetic aberrations and also overexpression of hTERT, and, in fact, the promoter of hTERT characterizes all malignant cells.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/219392
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