Resistance, either at the onset of the treatment or developed after an initial positive response, is a major limitation of antitumor therapy. In the case of platinum-based drugs, copper transporters have been found to interfere with drug trafficking by facilitating the import or favoring the platinum export and inactivation.
Monitoring Interactions inside Cells by Advanced Spectroscopies: Overview of Copper Transporters and Cisplatin
Lasorsa, Alessia;Natile, Giovanni
;Rosato, Antonio;Arnesano, Fabio
2018-01-01
Abstract
Resistance, either at the onset of the treatment or developed after an initial positive response, is a major limitation of antitumor therapy. In the case of platinum-based drugs, copper transporters have been found to interfere with drug trafficking by facilitating the import or favoring the platinum export and inactivation.File in questo prodotto:
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