Despite the evidence that certain viral satellites do not encode any functional product, they can either induce specific disease symptoms or alter (exacerbate or attenuate) symptoms that helper viruses induce in some hosts. Viral satellites that attenuate symptoms have the potential to be used as viral biocontrol agents. Satellite RNAs associated with cucumber mosaic virus (CMV) are well known for viral-symptom modulation properties, and in several instances ameliorative CMV satellites have been exploited to protect plants against hypervirulent CMV strains carrying satellite RNAs molecules that are necrogenic in tomato. Preinoculation and transgenesis of ameliorative CMV satellite variants have been tested under experimental and field conditions with encouraging results, but with a warning for potential risks for the spontaneous change of an ameliorative satRNA to a pathogenic variant and its dissemination by aphids.

Satellites as Viral Biocontrol Agents

Mascia, Tiziana
Investigation
;
Gallitelli, Donato
Writing – Review & Editing
2017-01-01

Abstract

Despite the evidence that certain viral satellites do not encode any functional product, they can either induce specific disease symptoms or alter (exacerbate or attenuate) symptoms that helper viruses induce in some hosts. Viral satellites that attenuate symptoms have the potential to be used as viral biocontrol agents. Satellite RNAs associated with cucumber mosaic virus (CMV) are well known for viral-symptom modulation properties, and in several instances ameliorative CMV satellites have been exploited to protect plants against hypervirulent CMV strains carrying satellite RNAs molecules that are necrogenic in tomato. Preinoculation and transgenesis of ameliorative CMV satellite variants have been tested under experimental and field conditions with encouraging results, but with a warning for potential risks for the spontaneous change of an ameliorative satRNA to a pathogenic variant and its dissemination by aphids.
2017
9780128014981
File in questo prodotto:
File Dimensione Formato  
Viroids and satellites Chapter 63.pdf

non disponibili

Descrizione: pdf del capitolo63 del volume
Tipologia: Documento in Versione Editoriale
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 365 kB
Formato Adobe PDF
365 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/208301
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 2
  • ???jsp.display-item.citation.isi??? ND
social impact