Logo Cardiorenal Medicine Original Paper The Renal Arterial Resistance Index Predicts Worsening Renal Function in Chronic Heart Failure Patients Iacoviello M.a · Monitillo F.b · Leone M.b · Citarelli G.b · Doronzo A.c · Antoncecchi V.c · Puzzovivo A.c · Rizzo C.b · Lattarulo M.S.b · Massari F.c · Caldarola P.c · Ciccone M.M.b Author affiliations Keywords: Chronic kidney diseaseSystemic disease and the kidneyGlomerular hemodynamics Cardiorenal Med 2017;7:42-49 https://doi.org/10.1159/000448405 Abstract Get article FullText PDF Login / Register Abstract Background/Aim: The renal arterial resistance index (RRI) is a Doppler measure, which reflects abnormalities in the renal blood flow. The aim of this study was to verify the value of RRI as a predictor of worsening renal function (WRF) in a group of chronic heart failure (CHF) outpatients. Methods: We enrolled 266 patients in stable clinical conditions and on conventional therapy. Peak systolic velocity and end diastolic velocity of a segmental renal artery were obtained by pulsed Doppler flow, and RRI was calculated. Creatinine serum levels were evaluated at baseline and at 1 year, and the changes were used to assess WRF occurrence. Results: During follow-up, 34 (13%) patients showed WRF. RRI was associated with WRF at univariate (OR: 1.13; 95% CI: 1.07-1.20) as well as at a forward stepwise multivariate logistic regression analysis (OR: 1.09; 95% CI: 1.03-1.16; p = 0.005) including the other univariate predictors. Conclusions: Quantification of arterial renal perfusion provides a new parameter that independently predicts the WRF in CHF outpatients. Its possible role in current clinical practice to better define the risk of cardiorenal syndrome progression is strengthened.
|Titolo:||The renal arterial resistance index predicts worsening renal function in chronic heart failure patients|
|Data di pubblicazione:||2017|
|Appare nelle tipologie:||1.1 Articolo in rivista|