Peripheral neuropathy (PN), the major neurological complication of chronic HCV infection, is frequently associated with mixed cryoglobulinemia (MC) and small-vessel systemic vasculitis. While humoral and cell-mediated immune mechanisms are suspected to act together in an aberrant immune response that results in peripheral nerve damage, the role of HCV remains largely speculative. The possible demonstration of HCV in peripheral nerve tissue would obviously assume important pathogenic implications.
HCV RNA genomic sequences and HCV-E2 glycoprotein in sural nerve biopsies from hcv-infected patients with peripheral neuropathy
RUSSI, SABINO;SANSONNO, Domenico Ettore;PAVONE, FABIO;LAULETTA, GIANFRANCO;
2017-01-01
Abstract
Peripheral neuropathy (PN), the major neurological complication of chronic HCV infection, is frequently associated with mixed cryoglobulinemia (MC) and small-vessel systemic vasculitis. While humoral and cell-mediated immune mechanisms are suspected to act together in an aberrant immune response that results in peripheral nerve damage, the role of HCV remains largely speculative. The possible demonstration of HCV in peripheral nerve tissue would obviously assume important pathogenic implications.File in questo prodotto:
File | Dimensione | Formato | |
---|---|---|---|
RUSSI, et al. HCV SURAL NERVE nan.12413.pdf
non disponibili
Descrizione: PDF
Tipologia:
Documento in Versione Editoriale
Licenza:
NON PUBBLICO - Accesso privato/ristretto
Dimensione
979.59 kB
Formato
Adobe PDF
|
979.59 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.