A convenient, versatile, and green CBS-asymmetric reduction of aryl and heteroaryl ketones has been developed by using the microreactor technology. The study demonstrates that it is possible to handle borane solution safely within microreactors and that the reaction performs well using 2-MeTHF as a greener solvent.
A convenient enantioselective CBS-reduction of arylketones in flow-microreactor systems
DE ANGELIS, SONIA;CARLUCCI, CLAUDIA;DEGENNARO, LEONARDO
;LUISI, Renzo
2016-01-01
Abstract
A convenient, versatile, and green CBS-asymmetric reduction of aryl and heteroaryl ketones has been developed by using the microreactor technology. The study demonstrates that it is possible to handle borane solution safely within microreactors and that the reaction performs well using 2-MeTHF as a greener solvent.File in questo prodotto:
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