Mucosal melanoma is a rare malignant neoplasm, more aggressive than the cutaneous counterpart. The first sign is usually a mass lesion that may display uniform pigmentation (black or brown) or a variegated discoloration (from black, brown to grey, purple and red), or may be depigmented. We report a case of oral malignant melanoma in a white man characterized by an unusual clinical appearance. A 65-year-old white man presented with an unusual lesion in the mouth. On physical examination, a heterogeneously pigmented lesion involving the soft and hard palates and the maxillary alveolar crest was seen (Fig. 1). The lesion had a nodular, nonpigmented, ulcerated central region (AM), measuring about 20 mm on its maximum diameter, surrounded by a nodular, ulcerated, pigmented area (UPM) and by other flat and not ulcerated pigmented lesions (PM), with an area resembling dysplastic naevi (DN). The patient did not smoke and had no history of trauma or chronic inflammation. He underwent hemimaxillectomy.
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|Titolo:||Oral malignant melanoma: immunopathological analysis of a multiphasic case|
|Data di pubblicazione:||2010|
|Appare nelle tipologie:||1.1 Articolo in rivista|