United States Patent Application 20080119719 Kind Code A1 Ascenzi; Maria-Grazia ; et al. May 22, 2008 TEMPLATES FOR ASSESSING BONE QUALITY AND METHODS OF USE THEREOF Abstract The present invention relates to the preparation and use of novel bone templates that can be prepared using a comprehensive approach to observing microstructural features of bone, including trabecular thickness and trabecular density. These features are assessed in regions of interest in a bone (e.g., proximal femur, distal femur, wrist, spine, etc.) as observed using digital radiographic techniques or clinical imaging, such as Dual Energy X-ray Absorptiometry (DEXA) and computed tomography (CT) scanners. The microstructural features are presented in the form of data based on scanning results and are also assessed and/or organized in terms of age, gender, race, pathology, clinical history, and other patient population parameters. The template can be used to assess bone quality, predict the likelihood of bone fracture, and evaluate prosthesis design and placement, based on an image of a corresponding subject bone, e.g. the bone of a patient. Inventors: Ascenzi; Maria-Grazia; (Santa Monica, CA) ; Favia; Angela; (Bari, IT) Assignee: The Regents of the University of California Oakland CA Class at Publication: 600/410; 435/4 International Class: C12Q 1/00 20060101 C12Q001/00; A61B 5/05 20060101 A61B005/05
Template for assessing bone quality and methods of use thereof
FAVIA, Angela
2007-01-01
Abstract
United States Patent Application 20080119719 Kind Code A1 Ascenzi; Maria-Grazia ; et al. May 22, 2008 TEMPLATES FOR ASSESSING BONE QUALITY AND METHODS OF USE THEREOF Abstract The present invention relates to the preparation and use of novel bone templates that can be prepared using a comprehensive approach to observing microstructural features of bone, including trabecular thickness and trabecular density. These features are assessed in regions of interest in a bone (e.g., proximal femur, distal femur, wrist, spine, etc.) as observed using digital radiographic techniques or clinical imaging, such as Dual Energy X-ray Absorptiometry (DEXA) and computed tomography (CT) scanners. The microstructural features are presented in the form of data based on scanning results and are also assessed and/or organized in terms of age, gender, race, pathology, clinical history, and other patient population parameters. The template can be used to assess bone quality, predict the likelihood of bone fracture, and evaluate prosthesis design and placement, based on an image of a corresponding subject bone, e.g. the bone of a patient. Inventors: Ascenzi; Maria-Grazia; (Santa Monica, CA) ; Favia; Angela; (Bari, IT) Assignee: The Regents of the University of California Oakland CA Class at Publication: 600/410; 435/4 International Class: C12Q 1/00 20060101 C12Q001/00; A61B 5/05 20060101 A61B005/05I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
