Cytochrome c oxidase(COX)catalyses the reduction of dioxygen to water by ferrocytochrome c.This reaction is coupled to the translocation of up to 1H+/e- 4H+/O2 across the coupling membrane from the inner to the outer aqueous phase (1,2). The catalytic cycle of COX can be divided into two phases: a reductive phase and an oxidative phase.A study is presented on the pHdependence of proton transfer of COX reconstituted in vesicles,associated with the oxidation phase,the reduction phase and the oxidation-rereduction rapid transition
PH DEPENDENCE OF THE VARIOUS PHASES OF THE PROTON PUMP OF CYTOCHROME C OXIDASE
CAPITANIO, Giuseppe;DE NITTO, Emanuele
2005-01-01
Abstract
Cytochrome c oxidase(COX)catalyses the reduction of dioxygen to water by ferrocytochrome c.This reaction is coupled to the translocation of up to 1H+/e- 4H+/O2 across the coupling membrane from the inner to the outer aqueous phase (1,2). The catalytic cycle of COX can be divided into two phases: a reductive phase and an oxidative phase.A study is presented on the pHdependence of proton transfer of COX reconstituted in vesicles,associated with the oxidation phase,the reduction phase and the oxidation-rereduction rapid transitionFile in questo prodotto:
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