In 1964, Tepperman and colleagues9 first established a mouse model of cholesterol gallstones by feeding a special lithogenic diet containing 1% cholesterol and 0.5% cholic acid. Later, Fujihira and colleagues10 found that at 8 weeks on the lithogenic diet, gallstone prevalence rates varied from 0% to 100% in 7 strains of mice
Lith genes and genetic analysis of cholesterol gallstone formation
PORTINCASA, Piero;
2010-01-01
Abstract
In 1964, Tepperman and colleagues9 first established a mouse model of cholesterol gallstones by feeding a special lithogenic diet containing 1% cholesterol and 0.5% cholic acid. Later, Fujihira and colleagues10 found that at 8 weeks on the lithogenic diet, gallstone prevalence rates varied from 0% to 100% in 7 strains of miceFile in questo prodotto:
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