Retinoids play important roles in the transcriptional activity of normal, degenerative and tumor cells. Retinoid analogues may be promising therapeutic agents for the treatment of immune disorders as different as type I diabetes and Systemic Lupus Erythematosus (SLE). In addition, the use of retinoids in cancer treatment has progressed significantly in the last two decades, thus numerous retinoid compounds have been synthesized and tested. In this article, the actual or potential use of retinoids as immune-modulators or tumor suppressive agents is discussed.

Retinoids: Novel Immunomodulators and tumor-suppressive agents?

CARRATU', Maria Rosaria;VACCA, Angelo
2012-01-01

Abstract

Retinoids play important roles in the transcriptional activity of normal, degenerative and tumor cells. Retinoid analogues may be promising therapeutic agents for the treatment of immune disorders as different as type I diabetes and Systemic Lupus Erythematosus (SLE). In addition, the use of retinoids in cancer treatment has progressed significantly in the last two decades, thus numerous retinoid compounds have been synthesized and tested. In this article, the actual or potential use of retinoids as immune-modulators or tumor suppressive agents is discussed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/134800
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