The synthesis of benzoleukotriene B-3 methyl ester has been easily achieved by a palladium-catalyzed dienylstannane/aryl halide coupling reaction. A selective and sequential electrophilic substitution with acyl chlorides, followed by a reduction reaction, leads to the title compound.
An Efficient Synthesis of the Methyl Ester of Benzoleukotriene B3, a Leukotriene B4 Analogue
BABUDRI, Francesco;PUNZI, Angela
1995-01-01
Abstract
The synthesis of benzoleukotriene B-3 methyl ester has been easily achieved by a palladium-catalyzed dienylstannane/aryl halide coupling reaction. A selective and sequential electrophilic substitution with acyl chlorides, followed by a reduction reaction, leads to the title compound.File in questo prodotto:
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