A convenient synthesis of 1,2,3-triazole-fused isoindolines and dihydroisoquinolines in good to excellent yield is reported, starting from easily available terminal alkynes and (2-haloaryl)alkylazides. The method is based upon a cycloaddition reaction, via click chemistry, followed by a transition metal-catalyzed functionalization of a CeH bond.

An easy synthetic approach to 1,2,3-triazole-fused heterocycles

PUNZI, Angela;
2010

Abstract

A convenient synthesis of 1,2,3-triazole-fused isoindolines and dihydroisoquinolines in good to excellent yield is reported, starting from easily available terminal alkynes and (2-haloaryl)alkylazides. The method is based upon a cycloaddition reaction, via click chemistry, followed by a transition metal-catalyzed functionalization of a CeH bond.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/13018
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