Gangliocytic paraganglioma (PG) is a rare neoplasm that characteristically occurs in the second portion of the duodenum with a predilection for Vater's ampulla. PG has a characteristic triphasic microscopic appearance with epithelioid cells, spindle cells, and ganglion cells; it was suggested that paraganglioma arises from an embryonic cell showing divergent differentiation. These tumors have a relatively benign course, although rarely tumors may metastatize or recur locally. We describe a case of simultaneous occurrence of PG in the periampullary region and in the mesenteric fat in a 54-year-old man, free of disease three years after surgical intervention. Duodenopancreatectomy, made for the periampullary lesion, in this case has been the only treatment possible. Copyright
Multiple localization of gangliocytic paraganglioma: A case report [Paragangliome gangliocytique à localisation multiple]
MARGARI A;D'ABBICCO, Dario;SERIO, Gabriella
2009-01-01
Abstract
Gangliocytic paraganglioma (PG) is a rare neoplasm that characteristically occurs in the second portion of the duodenum with a predilection for Vater's ampulla. PG has a characteristic triphasic microscopic appearance with epithelioid cells, spindle cells, and ganglion cells; it was suggested that paraganglioma arises from an embryonic cell showing divergent differentiation. These tumors have a relatively benign course, although rarely tumors may metastatize or recur locally. We describe a case of simultaneous occurrence of PG in the periampullary region and in the mesenteric fat in a 54-year-old man, free of disease three years after surgical intervention. Duodenopancreatectomy, made for the periampullary lesion, in this case has been the only treatment possible. CopyrightI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
