Primary intracranial dural B cell small lymphocytic lymphoma

Primary centrai nervous system non-Hodgkin lymphomas (PCNSNHL) are extranodal lymphomas arising within and confìned to the centrai nervous system (CNS). A frequency of 1-3% of ali nonHodgkin lymphomas and 2 - 4% of all brain neoplasms has been reported, with a particularly high incidence in the AIDS population, in transplant recipients and immunocompromised patients [1-3]. Meningeal involvement by malignant lymphomas is most often a manifestation of diffuse aggressive lymphomas [l - 3] while primary durai lymphomas with no associated cerebrai parenchyma lesions are rare diseases [4 - 22]. We describe a case of primary B celi small lymphocytic lymphoma (SIL) involving the dura of the frontoparietal and temporai regions, and include a review of the literature, performing a Medline search for cases of primary intracranial durai lymphoma [4-22]. A 44-year-old immunocompetent woman referred a 2-week history of headache, diplopia, blurring of vision, loss of concentrati an, and right eye exophthaimos. Cranial magnetic resonance imaging (MRI) disclosed a large right durai thickening frontal mass, which was hyperintense in T1 weighted images and hypointense in T2 sequences. The administration of Gadolinium diethylenetriamine pentaacetic acid (Gd DTPA) revealed a wide contrast enhanced area involving the meninges and initial invasion of the underlying brain on the right frontoparietal and sphenoidal regions