In this study, the results of haematological, virological and molecular analyses carried out on three cats with clinical signs of feline panleukopenia are reported. Parvovirus strains were detected in clinical samples of all cats by means of virus isolation and/or real-time PCR using a TaqMan probe. Unexpectedly, these feline strains were characterised as canine parvovirus variants 2a or 2c by MGB assays and/or sequence analysis of the VP2 gene. The detection of canine parvovirus strains in cats with overt disease poses some concerns about the efficacy of commercially-available feline panleukopenia vaccines against the canine viruses that have been repeatedly reported in cats.
Three cases of feline panleukopenia associated to canine parvovirus variants
CIRONE, Francesco;AMORISCO, Francesca;LOSURDO, MICHELE;DECARO, Nicola;DESARIO, COSTANTINA;BUONAVOGLIA, Canio
2012-01-01
Abstract
In this study, the results of haematological, virological and molecular analyses carried out on three cats with clinical signs of feline panleukopenia are reported. Parvovirus strains were detected in clinical samples of all cats by means of virus isolation and/or real-time PCR using a TaqMan probe. Unexpectedly, these feline strains were characterised as canine parvovirus variants 2a or 2c by MGB assays and/or sequence analysis of the VP2 gene. The detection of canine parvovirus strains in cats with overt disease poses some concerns about the efficacy of commercially-available feline panleukopenia vaccines against the canine viruses that have been repeatedly reported in cats.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
