There are few cases described in the world literature reporting an association of thymoma (with myasthenia gravis or not) with hyperparathyroidism. In these cases the hyperparathyroidism was due to the presence of an adenoma or hyperplasic parathyroid tissue either in the cervical region or in an ectopic intrathymic location. ((1-5)) In other cases the syndrome of hypercalcemia was due to the secretion of parathyroidrelated protein (PTHRP) ((6)) or parathyroid hormone (PTH) ((7)) by the thymoma itself. We report the first case, at the best of our knowledge, of a wide invasive malignant thymoma (type B3), associated with myasthenia gravis and hyperparathyroidism caused by parathyroid adenoma.
Association of a wide invasive malignant thymoma with miastenia gravis and primary hyperparathyroidism due to parathyroid adenoma: a case report and a review of the literature
TRIGGIANI, Vincenzo;GUASTAMACCHIA, Edoardo;RESTA, Francesco;SABBA', Carlo;
2006-01-01
Abstract
There are few cases described in the world literature reporting an association of thymoma (with myasthenia gravis or not) with hyperparathyroidism. In these cases the hyperparathyroidism was due to the presence of an adenoma or hyperplasic parathyroid tissue either in the cervical region or in an ectopic intrathymic location. ((1-5)) In other cases the syndrome of hypercalcemia was due to the secretion of parathyroidrelated protein (PTHRP) ((6)) or parathyroid hormone (PTH) ((7)) by the thymoma itself. We report the first case, at the best of our knowledge, of a wide invasive malignant thymoma (type B3), associated with myasthenia gravis and hyperparathyroidism caused by parathyroid adenoma.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
