We describe two patients with primary biliary cirrhosis (PBC) who presented with specific symptoms mimicking an undifferentiated connective tissue disease (arthromyalgia, fatigue, cutaneous lesions either morbillous-like or urticarial, the latter with an eosinophil infiltrate of upper dermis). Subsequent detection firstly of eosinophilia in the blood and secondarily of antimitochondrial antibodies with results of liver biopsy allowed a diagnosis of asymptomatic PBC. In our cases, a peculiar sign of early stage of PBC was represented also by the eosinophilia in the liver.
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|Titolo:||Cutaneous lesions as presenting symptoms of primary biliary cirrhosis: an undifferentiated connective tissue disease-like onset|
|Data di pubblicazione:||2006|
|Citazione:||Cutaneous lesions as presenting symptoms of primary biliary cirrhosis: an undifferentiated connective tissue disease-like onset / COVELLI M; FAVIA I; MARRONE M; IANNONE F; GENTILE A; LASTILLA G; LAPADULA G. - In: CLINICAL RHEUMATOLOGY. - ISSN 0770-3198. - 25(2006), pp. 919-922.|
|Appare nelle tipologie:||1.1 Articolo in rivista|