In spite of the vast knowledge of tooth development and of the various kinds of specialized bone/ tooth-associated cells, the characteristics and properties of their precursor cell populations present in the postnatal organism are little known, as is their possible therapeutic use. Taken together dental pulp stem cells (DPSCs) and periodontal ligament stem cells (PDLSCs) possess stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation. Regenerative medicine is based on stem cells, signals and scaffolds. Transplantation of those cells, which can be obtained from an easily accessible tissue resource and expanded in vitro, holds promise as a therapeutic approach for reconstruction of tissues and bone in vivo
In vitro stem cell cultures from human dental pulp and periodontal ligament: new prospects in dentistry
BALLINI A;CANTORE S;PAPA F;GRANO M;GRASSI FR
2007-01-01
Abstract
In spite of the vast knowledge of tooth development and of the various kinds of specialized bone/ tooth-associated cells, the characteristics and properties of their precursor cell populations present in the postnatal organism are little known, as is their possible therapeutic use. Taken together dental pulp stem cells (DPSCs) and periodontal ligament stem cells (PDLSCs) possess stem-cell-like qualities, including self-renewal capability and multi-lineage differentiation. Regenerative medicine is based on stem cells, signals and scaffolds. Transplantation of those cells, which can be obtained from an easily accessible tissue resource and expanded in vitro, holds promise as a therapeutic approach for reconstruction of tissues and bone in vivoI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.