PURPOSE: To report a masquerade syndrome secondary to multiple myeloma iris infiltration. DESIGN: Observational case report. METHODS: A 74-year-old Caucasian woman presenting with unilateral hypertensive uveitis and past medical history significant for multiple myeloma underwent aqueous cytology and a trabeculectomy with iridectomy. RESULTS: Cytology revealed atypical plasma cells in the aqueous while the anatomopathologic analysis of iris tissue demonstrated a substitution of the iris tissue by neoplastic plasma cells. After surgery and a new cycle of chemotherapy best-corrected visual acuity and intraocular pressure improved. CONCLUSIONS: Masquerade syndrome should always be considered in elderly uveitis. A correct diagnosis can be life-saving.

Hypertensive uveitis as a feature of multiple myeloma

GUERRIERO, Silvana;PISCITELLI, Domenico;SPECCHIA, Giorgina
2010-01-01

Abstract

PURPOSE: To report a masquerade syndrome secondary to multiple myeloma iris infiltration. DESIGN: Observational case report. METHODS: A 74-year-old Caucasian woman presenting with unilateral hypertensive uveitis and past medical history significant for multiple myeloma underwent aqueous cytology and a trabeculectomy with iridectomy. RESULTS: Cytology revealed atypical plasma cells in the aqueous while the anatomopathologic analysis of iris tissue demonstrated a substitution of the iris tissue by neoplastic plasma cells. After surgery and a new cycle of chemotherapy best-corrected visual acuity and intraocular pressure improved. CONCLUSIONS: Masquerade syndrome should always be considered in elderly uveitis. A correct diagnosis can be life-saving.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11586/116470
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