In tumors characterized by a high osteotropism, such as multiple myeloma, the measurement of bone metabolism markers is helpful in monitoring both severity and prognosis of the skeletal disease. Here, we review the pathophysiology of these markers including tartrate resistant acid phosphatase (TRAcP), which appears highly specific and closely related to the extent of myeloma bone lesions.
[Novel markers in osteo-oncology: the tartrate resistant acid phosphatase in myeloma bone disease]. FT Alla ricerca di nuovi marcatori in osteo-oncologia: la fosfatasi acida tartrato-resistente nella malattia ossea mielomatosa
Strippoli S;SILVESTRIS, Francesco
2011-01-01
Abstract
In tumors characterized by a high osteotropism, such as multiple myeloma, the measurement of bone metabolism markers is helpful in monitoring both severity and prognosis of the skeletal disease. Here, we review the pathophysiology of these markers including tartrate resistant acid phosphatase (TRAcP), which appears highly specific and closely related to the extent of myeloma bone lesions.File in questo prodotto:
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